Two postdoc scholarships in nanopore technology for protein detection at Uppsala University, Sweden (# of pos: 2)

Two postdoc scholarships in nanopore technology for protein detection at Uppsala University, Sweden (# of pos: 2)

Job title: Two postdoc scholarships in nanopore technology for protein detection at Uppsala University, Sweden (# of pos: 2)

Company: Uppsala University

Job description: Electrification, digitalisation and health technology are among the largest areas for the future in the conversion to sustainable societies. The Department of Electrical Engineering, Uppsala University, conducts successful research and education in the areas – renewable energy sources, electric vehicles, industrial IoT, 5G communication and wireless sensor networks as well as smart electronic sensors and medical systems. The Department of Electrical Engineering is an international workplace with around 130 employees that all contribute to important technical energy and health challenges at the Ångström Laboratory.

The positions will be with the Division of Solid-State Electronics, the Department of Electrical Engineering. Each position is meant for two year.

The research at the Division of Solid-State Electronics has three major focus areas: Electronics for Life Science and Medical Technologies, Electronics for Renewable Energy and Electronics for Brain-Inspired Computing. The technological base for our research is thin-film technology, semiconductor processing and semiconductor device technology using the in-house state-of-art cleanroom facilities, supported by device and process simulation as well as advanced electrical and optical characterisation. Our research objective is to develop technological solutions, from devices to small systems, for comprehensive analysis of genome, proteome, and transcriptome signatures of individuals, thereby enabling AI assisted predictive diagnosis and preemptive therapy. We strive for innovations such as near-body network systems, point-of-care electronic sensors and battery-free wearable and medical systems for continuous and real-time health monitoring. Such systems require mechanically flexible and soft devices including electronic and optoelectronic components, supported by thermoelectric or triboelectric/piezoelectric generators. Our research on renewable energy spans from nanophononics and hybrid materials for thermoelectrics to energy-efficient electronics. Finally, we have lately renewed our efforts to harness novel electronic device solutions towards a new computing paradigm.

Project description: This nanopore technology project aims at combining nanoelectronics and nanofluidics to enable protein detection in a parallel manner. The protein detection involves both electrical and optical means, while signal analysis requires both numerical simulation and machine learning. The positions involve fabrication of nanopores based on standard silicon technology that is the base for integrated circuits (IC chips), surface functionalisation of nanopores, handling of protein samples including specific labelling, electrical and optical characterisation, Comsol simulation and machine learning. The postdocs are expected to collaborate closely. The research will be performed in a multidisciplinary environment therein scientists of complementary backgrounds are available.

Duties:

  • Design and fabrication of nanopores in array form based on standard silicon technology in the cleanroom laboratory of Myfab-Uppsala.
  • Characterisation of the nanopores both by physical means with the assistance of a range of analysis methods such as SEM, TEM, and electrically-optically with the help of ionic current measurement, fluorescence measurement and calculation.
  • Characterisation of the nanopores for biomolecule analyses especially with protein molecules.
  • Simulation, based on Comsol or other software packages, for assistance in nanopore design as well as in interpretation of characterisation results.
  • Development of machine learning algorithms for interpretation and prediction of measurement results.

Requirements:

  • The applicant must hold a Doctoral degree in Technical Physics Electrical Engineering and / or Materials Science with a focus on semiconductor components and electronics, or a foreign degree that is deemed to correspond to such degrees.
  • Doctoral degree no older than three years.
  • Experience, supported by scientific publications, in silicon technology, nanopore fabrication and characterisation, modelling/simulation and/or machine learning.
  • Very good oral and written proficiency in English.

We put an emphasis on your personal qualities such as good collaboration and communication skills with other researchers. You should be purposeful, structured and able to work effectively both individually and in groups.

Additional qualifications: postdoc experience

Application: You should include a brief description of your research interests and relevant experience, a CV, copies of diplomas and certificates, thesis (or a draft thereof) and other relevant documents. You are encouraged to provide contact information to reference.

Stipend: 340 kSEK 1st year and 360 kSEK 2nd year, no income taxation.

Start time: 2021-09-01 or according to agreement.

Positions: Two years each.

Work degree of the positions: 100%

Announcement about the positions are provided by: Professor Shi-Li Zhang, telephone +46 18-471 7247, . Information about the Division of Solid-State Electronics can be found at .

Your application is welcome until the 31th of July 2021.

More Information

Expected salary:

Location: Uppsala

Job date: Sat, 03 Jul 2021 05:35:54 GMT

Apply for the job now!

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